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  6. Biosearch Technologies, Inc.

Biosearch Technologies, Inc.

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2199 S MCDOWELL BLVD EXT PETALUMA, CA 94954 Get Directions

(415) 883-8400

www.biosearchtech.com

Info@biosearchtech.com

Business Info

  • Founded 1992
  • Incorporated CA
  • Annual Revenue $43,171,990.00
  • Employee Count 120
  • Industries Biological Products, Except Diagnostic
  • Contacts Ronald M Cook

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Company Summary

The BHQplus(TM) probe is a novel compact probe for qPCR, modified with a duplex stabilizing technology and terminated with Biosearch's Black Hole Quencher(R) dye. What differentiates the BHQplus probe from other traditional probes is that it permits the design of shorter oligonucleotides, typically 15 - 25 bases in length, for detecting more difficult target sequences. The enhanced specificity of BHQplus probes make them perfect for genotyping single nucleotide polymorphisms.

BHQplus probes feature:

Scatterplot
Scatterplot of a BHQplus SNP Assay, resolving the respective genotypes

Looking for more information? View our poster Genotyping with BHQplus(TM) probes for additional details.

oSmall but powerful: duplex stabilizers permit the design of shorter dual-labeled probes
oHigh fidelity: shorter sequences offer an increased barrier against hybridizing to a mismatch
oProven performance: the Black Hole Quencher dye extinguishes fluorescence until target hybridization
oA mouse-click away: design your BHQplus probe through Biosearch's free, web-based RealTimeDesign(TM) software
oBottom line: An economical alternative for probe-based SNP Genotyping
Please be aware that sequences longer than 25 bases may have been designed as a traditional probe and are unlikely to work well in BHQplus form. Instead, consider ordering a BHQ(R) probe instead if such a sequence already has a predicted melting temperature of 70 ?C. Conversely, sequences shorter than 15 bases may have been designed as a Minor Groove Binder (MGB(TM)) probe and should first be analyzed for compatibility with the BHQplus chemistry. Please contact techsupport@biosearchtech.com with any questions regarding probe design.

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